meey replied: "bleeding... into anywhere of the body .. but if you monitor your coagulation factor rigidly, there should not be a problem since this drug is used in some conditions that are life saving."
Coumadin levels are too high, what foods/meds make them like this? My mother-in-law is on coumadin. We cannot keep her regulated. They have her on 5mg 1x daily and every other week she's up over 4 on her levels and then she has to take a few days without the medication and then get re-tested and then back on for a week. I think her problem is that she drinks too much (vodka with very little OJ). I'm thinking we need to increase her greens for the vitamin K to assist. I do her shopping and her shopping list consist of fruit, maybe one a day, very little vegies, but always a new jug of vodka and of course tons of sweets. This is driving me and my husband nuts! Any suggestions from someone that has dealt with this?
Unfortunately, she's 75 years old and is set in her ways. We've tried getting her to slow down, but she won't. I'm thinking the leafy fresh vegies will add clotting factors and then she won't be so thin on her blood. But, you have a point, maybe we should try NO coumadin, let her drink like she normally does and see if that's enough.....good point!
Lola replied: "Cumadin is a blood thinner, Why in the WORLD is she drinking like a fish?
She's is supposed to avoid the leafy greens. Is she diabetic? Clogged arteries. You need to notify her doctor that she drinking that much alcohol. THere's no point of her being on medication if she's going to counteract it with the liquor."
āNiki replied: "Alcohol is in itself a blood thinner... this is most likely the reason that her INR is so high. You could try counter acting it by giving her more of the foods that have high amounts of vitamin K such as: liver, broccoli, brussel sprouts, spinach, Swiss chard, coriander, collards, cabbage, and other green leafy vegetables.
Make sure that if you start introducing these foods into her diet that you do so on a regular basis. i.e. have her eat one of these foods every day... or two... or three. So long as it is kept at a constant.
You really should tell her doctor about the alcohol, though. That is bad news. If she falls or gets into an accident, there could be serious consequences because of her high INR.
I hope you the best of luck, and I am sorry for your situation. It must be difficult. If you have any questions, please IM or email me =)"
coumadin level too high will it make my joints hurt? if my level of coumadin is to high will it make my joints hurt
Cricket replied: "If its too high and you have bleeding into the joint it will be painful, but otherwise it should not be related to a high coumadin level."
why am I losing blood coumadin level go high? I had open heart surgery with 3 mechanical valves a year ago, I couldn't get coumadin level straightened out, I was on 2 mgs a day they increased me to 7.5mgs one day and 5 mgs the remaining 6 days. A week later they discovered I was low on blood and close to a transfusion, I'm weak, tired and ashy in the face area. I can't walk far with out getting pain in legs and lower back. Could it be I'm getting to much coumadin?
Ryan M replied: "Without knowing your whole medical history it's difficult to say what is happening. Your physicians are changing coumadin to get your bleeding time into a desired range, typically an INR value of 3-4. Coumadin affects platelet function, it should not depress your blood production. Other medications may reduce production of blood cells, though.
I don't think coumadin is the culprit here, but you should definitely get to a physician for these symptoms. Only a complete exam and history can lead to teh right diagnosis."
My mother who is 82 on coumadin her INR level has been high the past 2 blood draws.? She is on coumadin for DVT's. We can always tell when her level is elevated as she does not act like herself. Would a brain bleed cause the level to go up.
drbeat1023 replied: "No, a "brain bleed" or a hemorrhagic stroke may occur if her level is too high, but it would not cause further increases in her INR by itself. Coumadin causes this by inhibiting vitamin-K dependent blood clotting factors II, VII, IX and X.
Where are her INR levels when she has lab work done? For DVT prophylaxis, the level should remain between 2 and 3. If you've noticed mental status changes in your mother, I advise you to have her see a neurologist who could evaluate potential causes. It is unlikely that an increased INR could be blamed for this alone, unless it has caused some sort of brain trauma or somehow transiently causes it. Best of luck."
wishbone replied: "coumadin is one of the meds that we monitor in the lab frequently and it has to be adjusted accordingly. 2 possible causes of increased INR would be dehydration and renal problems."
Can an overdose caused by taking to much Coumadin cause kidney damage? My dad apparently was taking his medicine wrong, and his Coumadin level was way to high in April. All that has been resolved, but now his body is not metaolizing his medications correctly.
He is in the hospital now because his Dijoxin level got way to high and he nearly died.
Any suggestions on what would cause your body not to metobalize medications correctly would be great.
I guess I forgot to mention he does not have health insurance right now. He is disabled after double valve replacement and we are waiting until he is eligible for medicare in January. Until then he is on indigent care.
The doctors seem to be in hurry to treat him and are not looking deeply into what is going on. I guess I cannot blame them, because of no insurance. I am trying to do a little research myself so I will know what I should ask them to test for.
They will not test for anything unless we ask because the know he has no insurance. It also keeps us from being able to take him to a specialist, because we live in a small town and can only be treated in the county that is providing his indigent care.
Orinoco_W replied: "Coumadin is unlikely to cause kidney damage. It does thin the blood out so that bruising and bleeding can occur. If there is additional trauma to the kidney, then nasty bleeding can occur in the kidney (often seen as blood in the urine).
Digoxin is predominantly cleared renally.
Perhaps he has another cause of kidney problems - dehydration being the commonest.
Many other things can cause kidney troubles. Infections, prostate hypertrophy, kidney stones, drugs of various sorts, diabetes, autoimmune disease ...
Perhaps you should ask his doctors what has been going on?
The other things that cause poor metabolism of medications is liver disease (wiki says 16% hepatic metabolism ie 84% excreted unchanged), but digoxin is primarily cleared by the kidney."
Knut EU$$ replied: "he also could bleed to death...its a dangerous drug...be careful..."
lucyfire24 replied: "Many overdoses affect the liver and kidneys, because they are the organs that filter the blood and urine. Therefore, overloading those organs with anything (alcohol, medicine, drugs) can do permanent damage to them. The best thing he can do is stay in contact with his doctor to make him aware of the problems."
sveta_dr_mom replied: "As mentioned in other responses, Coumadin overdose can cause bleeding which can occur in any organ. As far as metabolizing medications, it's the job of the liver. It sounds like your father's liver might be having trouble doing its job."
xenoc replied: "Coumadin is perscribed to thin the blood for people who have had blood clots or are at risk for them. Its unlikely that too much Coumadin caused kidney damage. When the dose is too high it, it can cause bleeding which can be minor or serious like a stroke or gastrointestinal bleeding. The Coumadin dose has to be individualized for each person and is typically determined by performing a test called the INR test every so often. The dose of Coumadin is adjusted to keep the INR within a range that should keep the blood thin enough to reduce the risk of a blood clot but not so thin that the person should have a lot of bleeding. However, many things may interact with Coumadin and result in the INR being too high or low for the particular dose including different medications, foods and other medical problems.
Digoxin is primarily excreted from the body by the kidney so kidney damage can result in an increased level of digoxin in the body. So can a number of other drugs or other medical problems. The digoxin level in the body can also be checked by a blood test and the dose adjusted so that the level is maintained in an effective but generally safe level.
Sounds like your dad needs to be followed closely by his doctors to make sure that the doses of medicine he takes are adjusted to account for any new medications he may take, changes in his diet or any changes to his kidney function (or liver function since the liver also metabolizes many medications). A good website that provides comprehensive information on medications is at."
what are the three symptoms that a patient's blood level of coumadin is to high? blood level
Susan S replied: "Look in your textbook."
AdoreHim replied: "My husband is a diabetic and on coumadin as well- and there is really no symptoms , unfortunately- however he when he takes his blood sugar and he bleeds a lot, it is a good indication. Also have your pro-time and INR done often. It can fluctuate very quickly-"
I'm having difficulty maintaining correct Coumadin blood levels. Is anyone else having this problem? After 7 weekly blood tests for 'Coumandin level' it's either been too high or more often too low and not once in the 'therapeutic range'.
(My doctor keeps adjusting the dose weekly.)
Is anyone else having this problem and if so what has helped you get into your 'therapeutic range'.
I talked to the lab people where I get my weekly tests and they say that there are many people who find it difficult to find the right dose with results often too high or too low. And yet other people who have no problem at all.
I'm considering using another lab but I get the sense that it won't make any difference.
In general is this a common problem for many people on Coumadin? (getting/maintaining the correct dose level).
Any information is appreciated!
I've read a lot about nattokinase and the only downside seems to be to NOT take it with meds. like Coumadin.
Does anyone have any experience using nattokinase for blood clots?
If they tell me that I still have the blood clot after taking 3 months of Coumadin I may stop the Coumadin and try the nattokinase instead.
Any input is appreciated.
And thanks to all who've responded already, your comments are very helpful!!!
U Wish 2 B Me replied: "Aren't they doing the AT test on you? They shouldn't really be having a problem giving you the optimal dose. I would get a second opinion."
kumorifox replied: "Yes, it can be very tricky to adjust the levels properly. My grandmother needed it, and it took over three months to get it right for her."
Thomas replied: "Yes, it is often difficult to maintain a therapeutic INR [internationally standardized PT(Prothrombin Time)] on Warfarin(Coumadin). You should eat, take your med, exercise, sleep, wake, and have your lab drawn as close to the same time as possible every day(week for lab). Perhaps your doctor would want labs drawn 2 or 3 X's a week for a while? Good luck!"
DrGaellon replied: "Yes, for some patients, maintaining the correct blood level of warfarin is very difficult indeed. I have some patients that I test twice or thrice a week and still cannot maintain.
Make certain that you take your pill at the same time every day. Make certain also that you get your blood drawn at about the same time every day. Look around online to find lists of high- and low-Vitamin-K foods, and try to make sure you are getting about the same amount of Vitamin K in your diet every day."
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