zenithkid replied: "Previous answer from pharmacist is correct. Both contain pseudoephedrine, a decongestant that relieves stuffy noses by draining nasal passages. But they each contain a different anti histamine. Both are combination products, an anti histamine with a decongestant. Hence the brand names X-D....Y-D. D for Decongestant.
Some people have better results with one anti histamine, others do better on others. Use the combination product only if you have nasal congestion, otherwise, the single ingredient products Zyrtec and Allegra are all you need."
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